English German

Allergy diagnosis is performed to reveal the allergen(s) responsible for a patient´s symptoms. All too often, however, laboratory tests deliver positive results for allergens that are irrelevant for the given patient. This problematic situation is caused by cross-reactive IgE antibodies that lead to false positive results. Learn about the reasons for such false positive results and how to prevent them. Make sure your doctor is aware of the issue of “cross-reactive carbohydrate determinants” (short: CCDs) and draws diagnosis on correct laboratory results.

Proglycan aims at providing tools of highest quality for the prevention of false positive results in allergy diagnosis across analytical platforms in an affordable, readily available format.


cross reference:  Glycoscience related content (proglycan nomenclature for N-glycans and much more)


Regular serum-based allergy diagnosis (left panel) is affected by false positive results towards a plethora of allergens stemming from plants or insects. Every fourth to fifth patient is affected by such false positives (red characters).
Performing the same test procedure in the presence of a CCD-blocker (right panel) reduces false positives and thus delivers correct test results for all patients.